Skip to content
Unlabelled research vial
Illustration: a blank vial with the compound’s name set on it, not a product photo or a test result.

Migration and matrix

GHK-Cu

Also listed as Copper tripeptide-1, Prezatide copper, GHK copper

Copper(II) tripeptide complex

  • Cu(II) binding
  • ECM gene expression
Formula
Not quoted
Molar mass
Not quoted
CAS number
89030-95-5

Identity

What the molecule is, from its PubChem record. These are the figures a certificate of analysis should agree with.

Class
Copper(II) tripeptide complex
Sequence

H-GHK-OH · Cu(II)

  • The tripeptide Gly-His-Lys with one copper(II) ion bound.
Molecular formula
Not quoted See note
Molar mass
Not quoted See note
CAS number
89030-95-5

PubChem files the copper complex under several records that differ in charge state (for example C14H23CuN6O4⁺ in CID 71587328 and C14H22CuN6O4 in CID 165429100), so we don’t quote one formula or mass. The peptide on its own, GHK, is C14H24N6O4 at 340.38 g/mol (CID 73587).

Checked against PubChem on 27 September 2026. Molar mass is calculated from the formula with standard atomic weights and agrees with PubChem’s published molecular weight. In sequences, H- marks a free N-terminus, -OH a free C-terminal acid and -NH₂ a C-terminal amide.

Research context

GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine, which binds copper with high affinity. It is studied for its copper-binding chemistry and, in fibroblast cell culture, for changes in collagen and extracellular-matrix gene expression.

Research use only. Everything on Vialwise concerns research-grade material sold for laboratory and analytical use only. It is not a registered medicine, is not supplied for human or veterinary use, and nothing here is medical advice.

Storage and handling

  1. Store sealed lyophilised powder at −20 °C, dry and away from light.

  2. Let the vial reach room temperature before opening, so moisture doesn’t condense on the powder.

  3. The powder and its solutions are blue from the bound copper. Keep chelating agents such as EDTA out of the solvent, because they strip the copper from the peptide.

  4. Split the solution into single-use aliquots and keep them frozen, so no portion goes through repeated freeze–thaw.

General laboratory practice for this class of material; your institution’s own procedures come first. To work out concentration and aliquot volumes from a vial’s mass, use the reconstitution calculator. For the reasoning behind each step, read storing lyophilised peptides.

Published lab reports

Lab reports for GHK-Cu at Au Peptide Labs Our store

The one supplier whose full report list we have.

Open each lab-linked report on the lab’s own website to confirm it.

Other suppliers publish their reports on their own sites. Where each supplier publishes its COAs

Vialwise is published by APL Research Pty Ltd, which also runs Au Peptide Labs. Every supplier, ours included, is scored on the same published checklist. How we handle this

Any supplier

Check any supplier’s GHK-Cu COA

These checks take a few minutes and work the same on a report from any supplier, ours included. The walkthrough shows each one on a real Janoshik report.

How to verify a Janoshik COA
  1. Open it at the lab

    The report should load on the testing lab’s own website from the verify link or task number, not only as a PDF or screenshot from the supplier.

  2. Match the name

    The sample should be named GHK-Cu, Copper tripeptide-1 or Prezatide copper, or a clear equivalent. A different compound name means a different report.

  3. Match the mass

    If the report includes a mass-spectrometry result, compare it with the PubChem record for the exact form the supplier names. How HPLC and mass spec work.

  4. Match the vial

    The sample amount on the report should match the vial size you’re buying. A report on a different size or an older batch tells you less about the vial in front of you.

Related

Full library
  • Migration and matrix

    BPC-157

    Pentadecapeptide (15 residues)

    C62H98N16O221419.54 g/mol

  • Migration and matrix

    TB-500

    Thymosin β4 fragment (acetylated heptapeptide)

    C38H68N10O14889.01 g/mol